054. LOW DENSITY GRANULOCYTES IN ANCA VASCULITIS: PHENOTYPE AND FUNCTION

C-ANCA Positive Vasculitis in a Case of Amyloidosis

ANCA Glomerulonephritis and Vasculitis.

ANCA vasculitis has an associated autoimmune response that produces ANCAs that induce distinct pathologic lesions. Pauci-immune necrotizing and crescentic GN is a frequent component of ANCA vasculitis. ANCA vasculitis is associated with ANCA specific for myeloperoxidase (MPO-ANCA) or proteinase 3 (PR3-ANCA). A diagnosis of ANCA vasculitis should always specify the serotype as MPO-ANCA positive,...

Updates in ANCA-associated vasculitis.

Antineutrophil cytoplasm antibody (ANCA)-associated vasculitides are small-vessel vasculitides that include granulomatosis with polyangiitis (formerly Wegener's granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome). Renal-limited ANCA-associated vasculitides can be considered the fourth entity. Despite their rarity and still unknow...

Vasculitis and Multicenter Trial of Treatment in ANCA Associated Vasculitis

Renal Unit of Internal Medicine, Hachioji Medical Center, Tokyo Medical University, Tokyo; 1Laboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pharmacy, Tokyo; 2International Graduate School of Arts and Sciences, Yokohama City University, Yokohama, Japan. Masaharu Yoshida, MD, PhD Mariko Sasaki, MA Iwao Nakabayashi, MD, PhD Masakazu Akashi, MD Tomoh...

ANCA-positive vasculitis: Clinical implications of ANCA types and titers.

INTRODUCTION Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is an autoimmune disease that can affect multiple organs, the kidney being one of the most affected. Apart from the diagnostics value of ANCA, they have also been advocated as biomarkers of the disease activity. Recently, the genetic changes found in polyangiitis associated with serine-protease proteinase 3 (PR3)-ANC...